A common side effect of aging includes wrinkles around the mouth and lost elasticity; our skin just doesn’t bounce back as easily as it used to. Restylane Defyne® aims to fill and restore the face’s deepest lines to their original glory, without sacrificing the ability to project emotions. Smoothing out wrinkles is a useless accomplishment without the ability to retain a natural-looking face that can still be filled with emotion.

Similar to Restylane Refyne®, Restylane Defyne® is used to treat the areas around the mouth known as the nasolabial folds (laugh lines) and marionette lines.

Restylane Defyne® plumps and fills deep-set lines around the mouth with hyaluronic acid to improve elasticity and smooth out the skin. This state-of-the-art procedure can give patients back the aesthetic finish they deserve.

With over 95 years of combined experience, the staff at Shapiro Aesthetic Plastic Surgery and Skin Klinic is proud to offer Restylane Defyne® to our clients, led by Dr. Shapiro. If you are in the Scottsdale area in Arizona and are interested in receiving a Restylane Defyne® injection, contact us to schedule a consultation. We look forward to hearing from you!


What is Restylane Defyne®?

Restylane Defyne® is a dermal filler made of hyaluronic acid that works to replace the lost hyaluronic acid in the skin (less hyaluronic acid means less elasticity). Thanks to XpresHAn technology, Restylane Defyne® can last for up to 12 months after treatment, depending on post treatment care. Staying away from makeup is important after receiving an injectable to avoid infection and other side effects.

Restylane Defyne® acts immediately to create a desirable aesthetic effect and patients experience a relatively short recovery time. After treatment, patients reported noticing that their face looked natural when smiling and when at rest, as well as more accurately displaying the emotion they were feeling.

What are the Side Effects?

Every patient is different, but short-term side effects at the injection site may include:

  • Bruising
  • Itching
  • Pain/tenderness
  • Redness
  • Swelling

Side effects depend on the individual patient’s constitution as well as injection speed and injection volume. Consult with our medical team about any of your concerns regarding the side effects of Restylane Defyne®.

Meet Dr. Daniel Shapiro

A world-class plastic surgeon in a league of his own.

Dr. Shapiro is an award-winning, board-certified plastic surgeon with over 26 years of experience in his field. With impressive technical skill and a talent for creating natural-looking results, his practice has become a leading destination for discerning patients throughout the country.

Known for his compassion and honesty, Dr. Shapiro strives to educate his patients so that they are empowered about their care. He carefully explains the procedures, expected results, and techniques in a way that anyone can understand. Additionally, he personally guides his clients every step of the way – from the initial consultation to their post-operative care – to ensure an enjoyable experience and the best possible results.